DNA Synthesis Services

Oxford Genetics offers a range DNA Synthesis services, and can clone into the vector of your choice. 

 

 

Non-Cloned DNA

Cloned DNA

Format

Linear dsDNA fragment

dsDNA cloned into a plasmid

Gene Optimization

Optional

Optional

Plasmid Choice

NA

Oxford Genetics’ Catalogue Plasmid

Or

Customer Provided Plasmid

Yield

100 ng

5 µg

Turnaround Time

(0.5 – 3 kb)

15 days

30 days

Analysis

Sanger sequencing (pool)

Sanger sequencing

 

 

Additional Services

In addition to standard DNA synthesis, the following additional services are also available.

 

Gene Optimization

  • Coding sequence optimization of your gene of interest using our proprietary algorithms and in-house expertise.
  • High-throughput design and data processing (simultaneous optimisation of >1000 genes).
  • Modification of any DNA parameter, including balancing base composition, removal of palindromic and direct repeats, removal of restriction sites and consensus splice sites. 

Plasmid Optimization

  • Expression construct optimization, including Introduction of alternative promoter sequences; inclusion of optimal sequences in the 5’ UTR, 3’ UTR and poly-adenylation regions; choice of Kozak and stop codons; inclusion of exogenous genes to increase protein yield.