Group Leader – Molecular Biology


JOB TYPE: Permanent
WAGE: £50,000 – £60,000
HOURS: Full-time


Oxford Genetics is a specialist synthetic biology company offering a range of services and technologies to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. A unifying theme across the portfolio is expertise in DNA design, expression system optimisation, cell line development and engineering of viral delivery systems. We are located within purpose-fitted laboratories at the Oxford Science Park, just South of Oxford. We are in a phase of rapid expansion and are seeking highly motivated and enthusiastic scientists and engineers to join the team and help facilitate the next stage of our development as a company. We aim to be both innovative and entrepreneurial in everything we do – join us and contribute to this exciting journey!



The appointee will be involved in a range of internal platform development and commercial projects, across the wide remit of the Molecular Biology group. This will take on a number of specific responsibilities, notably expanding and developing Oxford Genetics plasmid and synthetic biology toolkit, further contributing to our multiple on-going programmes for viral vector design, engineering and bioproduction, and managing our expanding areas of DNA library design and construction. The Group Leader is expected to provide technical leadership within this area and will act as a subject matter expert within the company. The position will involve extensive interaction with both internal and external stakeholders, and the ability to show commitment to scientific development and innovation are considered essential. This position will interface with other Group Leaders within the company, in particular the leads for the Cell Line Development, Bioinformatics and Process Development teams. The position will report to the Chief Technology Officer.



  • Day to day management of activities within Molecular Biology laboratories
  • Direct line management of Molecular Biology group
  • To work closely with internal and external stakeholders to define project goals and deliverables, in line with planned project objectives
  • To keep up-to date with the scientific literature and developments in the field
  • Set an example to other colleagues, and to train and mentor junior staff
  • Provide project summaries and reporting, as required, along with taking overall responsibility for output from the group
  • Support and contribute to protection and assessment of intellectual property
  • Promote and suggest implementation of new methods, technologies and processes to ensure best practice
  • To ensure established quality standards are strictly adhered to, across all on-going activities



  • A Ph.D or DPhil in a relevant discipline.
  • Extensive knowledge of subject area, and ideally a strong network within academic or industry groups
  • Highly developed interpersonal, written and verbal skills, including the ability to give presentations and to speak to groups
  • High-level attention to detail
  • Experience in managing teams, both via direct line management and through matrix management
  • Ability to work under demanding conditions, and to cope with shifting priorities
  • Advanced knowledge of molecular biology techniques and approaches, ideally including automation of DNA assembly platforms, using Gibson, Golden gate methods as appropriate.
  • Understanding of in-silico tools for DNA design along with good ability to utilize statistical approaches to optimize processes and procedures
  • Advanced knowledge of viral vector genetics, and gene editing tools
  • Experience in constructing and analyzing DNA libraries



25 days Annual Leave plus Bank Holidays, Pension with matched employer contribution to 7%, Health Insurance, Group Life Cover, Child Care Voucher Scheme, Glasses Vouchers and a friendly working environment in an exciting and expanding young company.



We have offices in the UK and USA. This role will be located at The Oxford Science Park, just 4 miles south east of Oxford, with parking and good public transport links from Oxford. Our UK office address is: Oxford Genetics Ltd, Medawar Building, The Oxford Science Park, Oxford, OX4 4GA.



Candidates must be eligible to work in the United Kingdom without sponsorship.

Please send a CV. Your CV should include evidence that demonstrates how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks. Your application will be judged on the basis of how you demonstrate that you meet the selection criteria stated in the job description.



We provide all our staff with a welcoming and inclusive workplace that enables and empowers everyone to develop and deliver professional excellence. We recognise diversity is vital for innovation and creativity and value each individual’s contribution. Entry into employment with Oxford Genetics and further progression will be determined by personal merit and the application of criteria related to the duties of the role. The ability to perform the role will be the primary consideration on entry into employment and to successfully pass probation.



The appointment of the successful candidate will be subject to standard pre-employment screening, as applicable to the post. This will include right-to-work in the UK, proof of identity, references and health assessment.


To apply for the position then please send a cover letter and CV to