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The optimization of DNA and protein sequences, and the identification of proprietary new sequences, is another of the ways in which Oxford Genetics is utilizing its proprietary SnapFast™ platform.
Attaining expression of a gene can often be limited by the DNA sequence itself. This can be addressed to a certain degree by standard optimization methodologies such as codon usage, however, this may still not be enough for the most challenging sequences.
Oxford Genetics overcomes these limits by continually refining its design algorithms, and applying machine learning and complex statistical approaches to enable the optimization of DNA and protein sequences that demonstrate a significant increase in protein expression and virus expression.